Installation procedure
- Download the zip archive
- Go to the folder where you stored the zip file, click on it with the right mousebutton and choose "Extract All...".
- Go to the newly created folder that contains EN21Inst.msi and License.dat.
- Doubleclick on EN21Inst.msi to install EndNote. After installation you can install the .msp file for the latest update.
Do you have to enter a license code? Then you haven't followed the instructions above. It's not possible to install EndNote by starting the installation program directly from the zip file.